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Information
Janumet is a prescription medication that is used to lower blood sugar levels in patients who have type 2 diabetes.
Janumet is a prescription medication that is used to lower blood sugar levels in patients who have type 2 diabetes. Janumet contains two active ingredients: sitagliptin and metformin hydrochloride.
Sitagliptin, an oral anti-diabetic drug (OAD), works by inhibiting the release of glucose from the liver into your bloodstream after you eat food. This helps your body use insulin more efficiently and to better control your blood sugar levels. Metformin hydrochloride, another OAD commonly used to treat type 2 diabetes and polycystic ovary syndrome (PCOS), also helps your body make more sensitive to insulin so it will be able to use glucose more effectively
Janumet contains metformin and sitagliptin.
Janumet contains metformin and sitagliptin. Metformin is a biguanide. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor.
Metformin and sitagliptin are both oral medications that lower blood sugar in people with type 2 diabetes by reducing how much glucose your body absorbs from the food you eat and how much your liver makes, as well as increasing your sensitivity to insulin
Janumet is also indicated as add-on therapy to other oral antidiabetic agents, basal insulin or mealtime insulin when these treatments are inadequate for adequate glycemic control.
Janumet can be used with other medications. In addition to Janumet, you may need to take other oral antidiabetic agents, basal insulin or mealtime insulin. Janumet is also indicated as add-on therapy to other oral antidiabetic agents, basal insulin or mealtime insulin when these treatments are inadequate for adequate glycemic control.
Janumet should be administered with caution in patients with hypoglycemia unawareness and in patients who are on too large doses of metformin alone (more than 1 g/day).
Janumet may interact with birth control hormones, diuretics (water pills), rifampin, nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen, naproxen), pain medications, or steroids.
Janumet may interact with:
Birth control hormones. Janumet can decrease the effectiveness of birth control pills and other hormonal contraceptives, such as patches or implants. You’ll need to use a backup method of birth control while taking Janumet and for 1 month after you stop.
Diuretics (water pills). Some diuretic medicines (such as hydrochlorothiazide, chlorthalidone) may increase the amount of uric acid in your blood and cause gout attacks or kidney problems when taken with this medication. Other drugs used for high blood pressure or heart failure are also diuretics (but without known effects on uric acid levels), so be sure your doctor knows about any other medications you take before starting treatment with Janumet.
Rifampin This drug increases the risk that patiromer will cause low potassium levels in your blood. Your doctor should check your potassium level regularly during treatment if you’re taking patiromer while also taking rifampin because these two medications work well together to lower cholesterol levels; however, they can also cause serious side effects when taken together
Tell your doctor about all of the medications you’re taking including prescription and non-prescription medicines, vitamins and herbal supplements.
In addition to your diabetes medications, Janumet can also interact with other medications.
If you are taking birth control hormones, Janumet may cause your blood glucose to go low.
The combination of Janumet and rifampin has been shown to increase the risk of muscle breakdown in people with type 2 diabetes who are taking metformin. Rifampin is an antibiotic used for treating tuberculosis. Your doctor may need to adjust the dose of this drug if you take it while taking these medications together.
A common side effect of Janumet is hypoglycemia (low blood glucose). Diuretics such as hydrochlorothiazide or furosemide can elevate potassium levels in your body, which could cause your hypoglycemia symptoms to get worse if you take them at the same time as these drugs. Talk with your doctor about whether any other medicines you’re taking could affect how well Janumet works for you by causing hypoglycemia or other side effects that could make managing your diabetes more difficult
Janumet can help lower blood sugar levels in type 2 diabetic patients.
Janumet is a prescription medication used to treat type 2 diabetes. It contains two active ingredients, sitagliptin and metformin. Janumet is indicated as add-on therapy to other oral antidiabetic agents, basal insulin or mealtime insulin when these treatments are inadequate for adequate glycemic control.
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